Bibliographie pour la Médecine intégrée de Descartes

On voudrait folkloriser la Médecine intégrée de Descartes MiD ou MiDa pour « actualisée ».

La réduire aux cueilleuses de plantes. Aux guérisseuses du Mont Ventoux.

Mais la MiDa ce sont des milliers de publications de recherches académiques.

Nous avons identifié des centaines de publications académiques ciblées sur les thèmes de nos articles.
Les références sont dans trois lieux :
1. Dans le présent document, on a 90 % des références organisées par thème.
A trouver avec la fonction F = Find = Trouver du navigateur
Par exemple Massage
2. Certains articles ciblés ont leur propre bibliographie.
A trouver avec la requête agoramundi.fr/?s=university par exemple
3. La totalité des références avec leur résumé a été réunie dans un document de 250 pages.
Ce document permet de trouver toutes les références :
– soit pour une pathologie – exemple : inflammation sur 16 pages
– soit un organe – exemple brain (cerveau) sur 4 pages
– soit un item thérapeutique – exemple astragalus sur 20 pages

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Alerte sur la « justesse  » des articles WikiPédia

Exemple
L’article sur l’hyperperméabilité intestinale est bien documenté.

Cependant il est affecté d’un bandeau problématique.

Le bandeau qui est en haut de l’article « hyperperméabilité intestinale ».

Dans la MiDa il y a des charlatans, des illuminés, des escrocs comme dans toutes les médecines du monde.
Dans trop d’articles de WikiPédia, les savoirs de la MiDa sont :
– soit carrément supprimés
– soir diffamés en associant tel savoir avec telle escroquerie

Il convient donc :
– de chercher ailleurs quand les savoirs sont supprimés ou tronqués
– de « décoder » le processus de diffamation

En Octobre 2020, nous avons mené une action auprès des dirigeants de WikiPédia pour que ce problème soit résolu.

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Notre contribution à la MiDa se développent sur plusieurs sites en lignes :

Le présent site

Une Fabrique de Communs

Seconde médecine

En anglais Second medicine

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& = ancre

Lien direct vers la table des matières de la bibliographie

Depuis 2018, le chantier principal d’Une Fabrique de Communs c’est la santé des Français.

Pas la santé en général mais des scandales sanitaires que nous identifions, les uns après les autres.

Pas les scandales sanitaires en général mais un champ particulier.

La France est le seul pays au monde où le patient dispose seulement d’une Première médecine, une techno-médecine, une médecine à coup de molécules produites en usines, à coup de chirurgie sophistiquée utile ou inutile.
Descartes a affirmé avec force la nécessité d’une Seconde médecine.

Quand un patient est déclaré incurable par la Première médecine il doit pouvoir se tourner vers une Seconde médecine, une médecine de la seconde chance.

S’il a une main mangée par une bactérie que la Première médecine ne sait pas tuer, le patient doit pouvoir se tourner vers la phagothérapie.

S’il est attaqué par un virus il doit pouvoir être soigné par l’aromathérapie antivirale.

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Chaque jour des publications de recherches académiques sortent sur les thérapies naturelles qui nous intéressent : antiviraux, antibactériens, antifongiques, anti cellules malignes, modulation du système immunitaire – boost.

La présente bibliographie regroupe les bibliographies sur ces différents thèmes ainsi que celui des phages et de la phagothérapie.

Le jour du printemps 2021 on aura 250 références !

Organisation de la bibliographie

Je décide de ne pas classer les publications par auteur mais par thèmes.
On peut – bien évidemment – trouver un auteur via la fonction « Find » « F ».

Je mets des mots-clés – # – pour permettre de retrouver un article en fonction de la plante, etc. dont il traite.
Les vitamines sont codées #VitC, etc.
Si le nom de la plante est déjà dans le titre je le mets en gras ; dans ce cas je ne mets pas nécessairement de #.

Il faut donc faire la requêtre « Find » sans le #.
Exemple : Find artemisia

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Table des matières

Histoire des épidémies, etc. Lien
Le fonctionnement des dispositifs de santé et pour la santé – les scientisme en échec Lien

Seconde médecine
La question globale des thérapies dites traditionnelles, complémentaires et alternatives- Seconde médecine Lien
Général Lien
Ayur vedic, tibetan, chinese medicines Lien
Hypnose, transe, etc Lien
Jeûne prolongé Lien
Purge Lien
Dénouer les collages post accident, etc. MGCTCP Rolfing Lien

Plantes, etc.
Plantes antivirales, antibactériennes et antifongiques Lien
Champignons qui boostent les globules tueurs et font + Lien
Plantes qui boostent le système immunitaire Lien
Plantes qui boostent les globules tueurs Lien
Plantes qui favorisent l’apoptose – suicide – des cellules malignes Lien
Nigelle Lien
Artemisia Armoise Lien
Plantes et cellules malignes – divers Lien
Graviola Lien
Solanum, swertia, cichorium, smilax, etc.
Papaya Lien
Q10, garlic, aloe, ginseng, uncaria, grenade, calendula
Emblica, tea, neurolaena, curcuma, polygonum, spirulina,
Berries, cranberries, blueberry, ligonberry
Sophora, cannelle, girofle, thym, sauge, lavande, romarin, rue
Garlic, allium, avocado, cocoa, algae, barley-orge, alfalfa, mollusques, oeufs, polen, chardon marie, avoine
Camphor, arctium-bardane, rheum-rhubarbe, DMSO, carvacol, muscade, urtica
Clay, zeolite, argile Lien
Phages et phagothérapie contre bactéries multirésistantes aux antibiotiques Lien
Chloroquine Lien

Pathologies
Les bactéries multirésistantes aux antibiotiques Lien
Lyme Lien
Dermato Lien
Yeux Lien
Vésicule biliaire Lien
Le déclenchement des tumeurs, leucémies et autres maladies par les chocs émotionnels Lien
Emballement immunitaire ; cytokines
Cas cliniques cellules malignes Lien

Divers
Analyse des pratiques médicales – Première médecine Lien
Seconde médecine Lien

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Histoire des épidémies, etc.

François Gérard 1935 Notice sur le choléra-morbus observé à Avignon, pendant les mois de juillet, août et septembre Imprimerie Rastour https://gallica.bnf.fr/ark:/12148/bpt6k54266896

Jean-Louis Charvet L’épidémie de choléra de 1884 à Avignon et à Toulon Academia

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Le fonctionnement des dispositifs de santé et pour la santé – les scientisme en échec

L’OPECST, trente ans d’évaluations des choix scientifiques et technologiques au Parlement
Entretien avec la Sénatrice Marie-Christine Blandin

Ravelli Quentin, « Résistances aux antibiotiques : la fin du scientisme de l’innovation », Bulletin d’histoire et d’épistémologie des sciences de la vie, 2014/2 (Volume 21), p. 149-161. DOI : 10.3917/bhesv.212.0149. URL : https://www.cairn.info/revue-bulletin-d-histoire-et-d-epistemologie-des-sciences-de-la-vie-2014-2-page-149.htm

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La question globale des thérapies dites traditionnelles, complémentaires et alternatives = MiDa

Hollenberg D, Zakus D, Cook T, Xu XW. Re-positioning the role of traditional, complementary and alternative medicine as essential health knowledge in global health: do they still have a role to play? World Health Popul. 2008;10(4):62-75. PMID: 19550163. https://pubmed.ncbi.nlm.nih.gov/19550163/

Ministère de la santé France Les pratiques de soins non conventionnelles Médecines complémentaires / alternatives / naturelles
https://solidarites-sante.gouv.fr/soins-et-maladies/qualite-des-soins-et-pratiques/securite/article/les-pratiques-de-soins-non-conventionnelles

Redvers N, Blondin B. Traditional Indigenous medicine in North America: A scoping review. PLoS One. 2020 Aug 13;15(8):e0237531. doi: 10.1371/journal.pone.0237531. PMID: 32790714; PMCID: PMC7425891. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425891/

Oyinlola Oyebode, Ngianga-Bakwin Kandala, Peter J Chilton, Richard J Lilford, Use of traditional medicine in middle-income countries: a WHO-SAGE study, Health Policy and Planning, Volume 31, Issue 8, October 2016, Pages 984–991, https://doi.org/10.1093/heapol/czw022 https://academic.oup.com/heapol/article/31/8/984/2198144

Le département de l’OMS pour les médecines « autres » WHO en anglais

Sciences direct : revue de publications sur la traditional medecine
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Joensuu H. Systemic chemotherapy for cancer: from weapon to treatment. Lancet Oncol. 2008 Mar;9(3):304. doi: 10.1016/S1470-2045(08)70075-5. PMID: 18308256. https://pubmed.ncbi.nlm.nih.gov/18308256/ #chimiothérapie

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MGCTCP, rolfing

Landels B, Studies BH. Structural Integration Case Report: a Global Intervention Challenging the Limitations of Local Rehabilitation. Int J Ther Massage Bodywork. 2021 Mar 1;14(1):39-48. PMID: 33654505; PMCID: PMC7892333. https://pubmed.ncbi.nlm.nih.gov/33654505/ #Rolfing

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Le déclenchement des tumeurs, leucémies et autres maladies par les chocs émotionnels

Chida Y, Hamer M, Wardle J, Steptoe A. Do stress-related psychosocial factors contribute to cancer incidence and survival? Nat Clin Pract Oncol. 2008 Aug;5(8):466-75. doi: 10.1038/ncponc1134. Epub 2008 May 20. PMID: 18493231. https://pubmed.ncbi.nlm.nih.gov/18493231/

Reiche EM, Nunes SO, Morimoto HK. Stress, depression, the immune system, and cancer. Lancet Oncol. 2004 Oct;5(10):617-25. doi: 10.1016/S1470-2045(04)01597-9. PMID: 15465465. https://pubmed.ncbi.nlm.nih.gov/15465465/

Quand le cancérologue Hamer déclenche un cancer suite à la mort de son fils
Plusieurs ouvrages d’où l’on peut tirer des éléments intéressants

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Plantes antivirales, antibactériennes et antifongiques

Effet vis à vis de la protéine spike & angiotensin-converting enzyme 2 (ACE2) receptor

Kulkarni SA, Nagarajan SK, Ramesh V, Palaniyandi V, Selvam SP, Madhavan T. Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein. J Mol Struct. 2020 Dec 5;1221:128823. doi: 10.1016/j.molstruc.2020.128823. Epub 2020 Jul 4. PMID: 32834111; PMCID: PMC7334662.
Plantes des familles #Lamiaceae, #Lauraceae, #Myrtaceae, #Apiaceae, #Geraniaceae et #Fabaceae

Senthil Kumar KJ, Gokila Vani M, Wang CS, Chen CC, Chen YC, Lu LP, Huang CH, Lai CS, Wang SY. Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells. Plants (Basel). 2020 Jun 19;9(6):770. doi: 10.3390/plants9060770. PMID: 32575476; PMCID: PMC7355681.
#geranium #lemon

Varghese PM, Tsolaki AG, Yasmin H, Shastri A, Ferluga J, Vatish M, Madan T, Kishore U. Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies. Immunobiology. 2020 Nov;225(6):152008. doi: 10.1016/j.imbio.2020.152008. Epub 2020 Aug 19. PMID: 33130519; PMCID: PMC7434692.

Intéressant pour l’explication du rôle de Spike.

Fin publications sur spike

Korkmaz H. Could Sumac Be Effective on COVID-19 Treatment? J Med Food. 2021 Jun;24(6):563-568. doi: 10.1089/jmf.2020.0104. Epub 2020 Aug 18. PMID: 32816615.
#Sumac

Panikar S, Shoba G, Arun M, Sahayarayan JJ, Usha Raja Nanthini A, Chinnathambi A, Alharbi SA, Nasif O, Kim HJ. Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties. J Infect Public Health. 2021 May;14(5):601-610. doi: 10.1016/j.jiph.2020.12.037. Epub 2021 Feb 10. PMID: 33848890; PMCID: PMC7874929.
#Eucalyptus and # Corymbia

Amparo TR, Seibert JB, Silveira BM, Costa FSF, Almeida TC, Braga SFP, da Silva GN, Dos Santos ODH, de Souza GHB. Brazilian essential oils as source for the discovery of new anti-COVID-19 drug: a review guided by in silico study. Phytochem Rev. 2021 Apr 13:1-20. doi: 10.1007/s11101-021-09754-4. Epub ahead of print. PMID: 33867898; PMCID: PMC8042356.
# 45 plantes

Burton MJ, Clarkson JE, Goulao B, Glenny AM, McBain AJ, Schilder AG, Webster KE, Worthington HV. Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID-19 infection to improve patient outcomes and to protect healthcare workers treating them. Cochrane Database Syst Rev. 2020 Sep 16;9(9):CD013627. doi: 10.1002/14651858.CD013627.pub2. PMID: 32936948; PMCID: PMC8187985.
#artemisin #curcumin

Stathis C, Victoria N, Loomis K, Nguyen SA, Eggers M, Septimus E, Safdar N. Review of the use of nasal and oral antiseptics during a global pandemic. Future Microbiol. 2021 Jan;16(2):119-130. doi: 10.2217/fmb-2020-0286. Epub 2021 Jan 19. PMID: 33464122; PMCID: PMC7842245.

Grigore A, Cord D, Tanase C, Albulescu R. Herbal medicine, a reliable support in COVID therapy. J Immunoassay Immunochem. 2020 Nov 1;41(6):976-999. doi: 10.1080/15321819.2020.1862867. Epub 2020 Dec 26. PMID: 33356860.

Valussi M, Antonelli M, Donelli D, Firenzuoli F. Appropriate use of essential oils and their components in the management of upper respiratory tract symptoms in patients with COVID-19. J Herb Med. 2021 Aug;28:100451. doi: 10.1016/j.hermed.2021.100451. Epub 2021 Mar 26. PMID: 33816085; PMCID: PMC7997686.

Hensel A, Bauer R, Heinrich M, Spiegler V, Kayser O, Hempel G, Kraft K. Challenges at the Time of COVID-19: Opportunities and Innovations in Antivirals from Nature. Planta Med. 2020 Jul;86(10):659-664. doi: 10.1055/a-1177-4396. Epub 2020 May 20. PMID: 32434254; PMCID: PMC7356065.

Boukhatem MN, Setzer WN. Aromatic Herbs, Medicinal Plant-Derived Essential Oils, and Phytochemical Extracts as Potential Therapies for Coronaviruses: Future Perspectives. Plants (Basel). 2020 Jun 26;9(6):800. doi: 10.3390/plants9060800. PMID: 32604842; PMCID: PMC7356962.

Carrouel F, Gonçalves LS, Conte MP, Campus G, Fisher J, Fraticelli L, Gadea-Deschamps E, Ottolenghi L, Bourgeois D. Antiviral Activity of Reagents in Mouth Rinses against SARS-CoV-2. J Dent Res. 2021 Feb;100(2):124-132. doi: 10.1177/0022034520967933. Epub 2020 Oct 22. PMID: 33089717; PMCID: PMC7582358.

Wilkin PJ, Al-Yozbaki M, George A, Gupta GK, Wilson CM. The Undiscovered Potential of Essential Oils for Treating SARS-CoV-2 (COVID-19). Curr Pharm Des. 2020;26(41):5261-5277. doi: 10.2174/1381612826666201015154611. PMID: 33059564.

Asif M, Saleem M, Saadullah M, Yaseen HS, Al Zarzour R. COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties. Inflammopharmacology. 2020 Oct;28(5):1153-1161. doi: 10.1007/s10787-020-00744-0. Epub 2020 Aug 14. Erratum in: Inflammopharmacology. 2021 Apr;29(2):577. PMID: 32803479; PMCID: PMC7427755.

Wani AR, Yadav K, Khursheed A, Rather MA. An updated and comprehensive review of the antiviral potential of essential oils and their chemical constituents with special focus on their mechanism of action against various influenza and coronaviruses. Microb Pathog. 2021 Mar;152:104620. doi: 10.1016/j.micpath.2020.104620. Epub 2020 Nov 16. PMID: 33212200.

Blanchard, J.-. Cinnamomum camphora à cinéole (ravintsara), une plante au service de la prévention des infections nosocomiales en milieu hospitalier ?. Phytothérapie 5, 15–20 (2007). https://doi.org/10.1007/s10298-007-0202-1Published26 April 2007 Issue DateFebruary 2007 DOI https://doi.org/10.1007/s10298-007-0202-1

Nathalie Koziol. Huiles essentielles d’Eucalyptus globulus, d’Eucalyptus radiata et de Corymbia
citriodora : qualité, efficacité et toxicité. Sciences pharmaceutiques. 2015. ffhal-01733789f
https://hal.univ-lorraine.fr/hal-01733789/document

Schnitzler P, Schön K, Reichling J. Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture. Pharmazie. 2001;56(4):343–347.
https://pubmed.ncbi.nlm.nih.gov/11338678-antiviral-activity-of-australian-tea-tree-oil-and-eucalyptus-oil-against-herpes-simplex-virus-in-cell-culture/ #Melaleuca alternifolia

Oleg V. Pyankov, Evgeny V. Usachev, Olga Pyankova & Igor E. Agranovski (2012) Inactivation of Airborne Influenza Virus by Tea Tree and Eucalyptus Oils, Aerosol Science and Technology, 46:12, 1295-1302, DOI: 10.1080/02786826.2012.708948
https://www.tandfonline.com/doi/full/10.1080/02786826.2012.708948 #Melaleuca alternifolia

Garozzo A, Timpanaro R, Bisignano B, Furneri PM, Bisignano G, Castro A. In vitro antiviral activity of Melaleuca alternifolia essential oil. Lett Appl Microbiol. 2009;49(6):806–808. doi:10.1111/j.1472-765X.2009.02740.x
https://pubmed.ncbi.nlm.nih.gov/19843207-in-vitro-antiviral-activity-of-melaleuca-alternifolia-essential-oil/ #tea tree

Etude de la variation de la composition chimique de l’huile essentielle de Niaouli (Melaleuca viridiflora Sol. Ex Gaertn. ) de Madagascar par Armand René Panja Ramanoelina

SFE Malaleuca viridiflora http://www.ethnopharmacologia.org/recherche-dans-prelude/?plant_id=3900

Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species Monica R. Loizzo, Antoine M. Saab, Rosa Tundis, Giancarlo A. Statti, Francesco Menichini, Ilaria Lampronti, Roberto Gambari, Jindrich Cinatl, Hans Wilhelm Doerr First published:20 March 2008 https://doi.org/10.1002/cbdv.200890045
https://onlinelibrary.wiley.com/action/showCitFormats?doi=10.1002%2Fcbdv.200890045 #Laurus nobilis #Juniperus oxycedrus ssp. oxycedrus #Thuja orientalis #Cupressus sempervirens ssp. pyramidalis #Pistacia palaestina #Salvia officinalis #Satureja thymbra

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Plantes qui boostent le système immunitaire

Liu YX, Bai JX, Li T, Fu XQ, Guo H, Zhu PL, Chan YC, Chou JY, Yin CL, Li JK, Wang YP, Chen YJ, Yu ZL. A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment. Pharmacol Res. 2019 Apr;142:115-126. doi: 10.1016/j.phrs.2019.02.020. Epub 2019 Feb 20. PMID: 30797070.

Auyeung KK, Han QB, Ko JK. Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers. Am J Chin Med. 2016;44(1):1-22. doi: 10.1142/S0192415X16500014. PMID: 26916911.

Li Y, Li X, Cuiping C, Pu R, Weihua Y. Study on the Anticancer Effect of an Astragaloside- and Chlorogenic Acid-Containing Herbal Medicine (RLT-03) in Breast Cancer. Evid Based Complement Alternat Med. 2020 Jun 10;2020:1515081. doi: 10.1155/2020/1515081. PMID: 32595723; PMCID: PMC7305538. https://pubmed.ncbi.nlm.nih.gov/32595723/ #lonicera #astragale

« Astragalus ». NCCIH National Center for Complementary and Integrative Health, US National Institutes of Health. 29 November 2016. Retrieved 1 July 2019 #astragale

Su, Guobin; Chen, Xiankun; Liu, Zhuangzhu; Yang, Lihong; Zhang, La; Stålsby Lundborg, Cecilia; Wen, Zehuai; Guo, Xinfeng; Qin, Xindong; Liang, Jueyao; Liu, Xusheng (1 December 2016). « Oral (Huang qi) for preventing frequent episodes of acute respiratory tract infection in children »Cochrane Database of Systematic Reviewsdoi:10.1002/14651858.CD011958.pub2PMC 6463872PMID 27905672. #astragalus #astragale

Liu ZG, Xiong ZM, Yu XY. [Effect of astragalus injection on immune function in patients with congestive heart failure]Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 May;23(5):351-3. #astragale

Gu W, Yang YZ, He MX. [A study on combination therapy of Western and traditional Chinese medicine of acute viral myocarditis]. . Zhongguo Zhong Xi Yi Jie He Za Zhi. 1996 Dec;16(12):713-6. #coenzyme Q10 #ubiquinol #astragalus #astragale

Huang ZQ, Qin NP, Ye W. [Effect of Astragalus membranaceus on T-lymphocyte subsets in patients with viral myocarditis]Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Jun;15(6):328-30. #astragale

Yan HJ. [Clinical and experimental study of the effect of kang er xin-I on viral myocarditis]. . Zhong Xi Yi Jie He Za Zhi. 1991 Aug;11(8):468-70, 452. #lonicera japonica #ophiopogon japonicus #astragalus #astragale

14. Liu JP, Yang M, Du XM. Herbal medicines for viral myocarditisCochrane Database Syst Rev. 2004;(3):CD003711. #review #revue de publications

Wu J, Wang YX, et alEffect of astragalus injection on serious abdominal traumatic patients’ cellular immunityChin J Integr Med. 2006 Mar;12(1):29-31. #astragale

Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia. Wang MS, Li J, Di HX. Chin J Integr Med. 2007 Jun;13(2):98-102. #astragale

Weng XS. [Treatment of leucopenia with pure Astragalus preparation–an analysis of 115 leucopenic cases]Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Aug;15(8):462-4. #astragale

Upton R, Ed. Astragalus Root: analytical, quality control, and therapeutic monograph. American Herbal Pharmacopoeia. États-Unis, 1999. #astragale

AMR Astragalus membranaceus. Monograph. [No authors listed] Altern Med Rev. 2003 Feb;8(1):72-7. Review. Texte intégral : http://www.thorne.com #astragale

Immune system effects of echinacea, ginseng, and astragalus: a review. Block KI, Mead MN. Integr Cancer Ther. 2003 Sep;2(3):247-67. Review. #astragale #echinacee

The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: a pilot study. Zwickey H, Brush J, Iacullo CM et al. Phytother Res. 2007 Nov;21(11):1109-12. #reglisse #astragale

The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. Brush J, Mendenhall E, Guggenheim A, et alPhytother Res. 2006 Aug;20(8):687-95. #reglisse

Tafazoli A. Echinacea for Cancer Patients: To Give or Not to Give. Complement Med Res. 2020;27(2):112-116. doi: 10.1159/000503025. Epub 2019 Oct 3. PMID: 31581155. https://pubmed.ncbi.nlm.nih.gov/31581155/

Shang X, Pan H, Li M, Miao X, Ding H. Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. J Ethnopharmacol. 2011 Oct 31;138(1):1-21. doi: 10.1016/j.jep.2011.08.016. Epub 2011 Aug 16. PMID: 21864666; PMCID: PMC7127058. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127058/ #flos lonicera

J.A. Taylor, W. Weber, L. Standish, H. Quinn, J. Goesling, M. McGann, C. Calabrese, « Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial », JAMA, vol. 290, no 21,‎ 2003, p. 2824-2830 (PMID 14657066lire en ligne [archive], consulté le 18 février 2015) #echinacee

Ronald B. Turner, M.D., Rudolf Bauer, Ph.D., Karin Woelkart, Thomas C. Hulsey, D.Sc., and J. David Gangemi, Ph.D.An Evaluation of Echinacea angustifolia in Experimental Rhinovirus Infections The New England Journal of Medicine Volume 353:341-348 July 28, 2005 version en ligne [archive] #echinacee

Marlies Karsch-Völk, Bruce Barrett, Klaus Linde, « Echinacea for Preventing and Treating the Common Cold », JAMA, vol. 313, no 6,‎ 2015, p. 618-619 (résumé [archive]) #echinacee

V. Goel, R. Lovlin, R. Barton, M.R. Lyon, R. Bauer, T.D. Lee, T.K. Basu, « Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trial », Journal of clinical pharmacy and therapeutics, vol. 29, no 1,‎ 2004, p. 75-83 (PMID 14748902lire en ligne [archive], consulté le 18 février 2015) #echinacee

Sachin A. Shah, Stephen Sander, C. Michael White, Mike Rinaldi, Dr. Craig I. Coleman, « Evaluation of echinacea for the prévention and treatment of the momon cold: a meta-analysis », The Lancet, vol. 7, no 7,‎ 2007, p. 473-480. #echinacee

Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017;9(11):1211. Published 2017 Nov 3. doi:10.3390/nu9111211
https://www.researchgate.net/publication/320843979_Vitamin_C_and_Immune_Function #VitC

Harvard Can vitamin C prevent a cold?
https://www.health.harvard.edu/cold-and-flu/can-vitamin-c-prevent-a-cold #VitC

Jafari D., Esmaeilzadeh A., Mohammadi-Kordkhayli M., Rezaei N. (2019) Vitamin C and the Immune System. In: Mahmoudi M., Rezaei N. (eds) Nutrition and Immunity. Springer, ChamFirst Online31 July 2019 DOI https://doi.org/10.1007/978-3-030-16073-9_5 Springer, Cham Print ISBN978-3-030-16072-2 Online ISBN978-3-030-16073-9 #VitC

Stéphanie Gerbaka. Le cassis (Ribes nigrum L.) : études botanique, chimique et effets thérapeutiques.
Sciences pharmaceutiques. 2013. ffdumas-00844030f

Ashigai H, Komano Y, Wang G, Kawachi Y, Sunaga K, Yamamoto R, Takata R, Miyake M, Yanai T. Polysaccharide from black currant (Ribes nigrum L.) stimulates dendritic cells through TLR4 signaling. Biosci Microbiota Food Health. 2017;36(4):141-145. doi: 10.12938/bmfh.16-029. Epub 2017 Jul 4. PMID: 29038769; PMCID: PMC5633528. #cassis

Sforcin JM. Propolis and the immune system: a review. J Ethnopharmacol. 2007;113(1):1–14. doi:10.1016/j.jep.2007.05.012
https://www.researchgate.net/publication/6257328_Propolis_and_the_immune_system_A_review

K. Wolska*, A. Górska, K. Antosik and K. Ługowska Immunomodulatory Effects of Propolis and its Components on Basic Immune Cell Functions

Sim W, Barnard RT, Blaskovich MAT, Ziora ZM. Antimicrobial Silver in Medicinal and Consumer Applications: A Patent Review of the Past Decade (2007⁻2017). Antibiotics (Basel). 2018 Oct 26;7(4):93. doi: 10.3390/antibiotics7040093. PMID: 30373130; PMCID: PMC6315945.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315945/ #argent

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Champignons qui boostent les globules tueurs et font +

Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/

Schaeffer K, Wenner C, Novack J417 REISHI AND POLYSACCHARIDE-KRESTIN AS IMMUNE MODULATORS: DIFFERENTIAL EFFECTS OF MUSHROOM EXTRACTS ON BOTH CYTOKINE SECRETION AND INDUCTION OF T REGULTORY CELLS FROM HUMAN PERIPHERAL BLOOD.Journal of Investigative Medicine 2007;55:S144. #Ganoderma lingzhi

Kladar NV, Gavarić NS, Božin BN. Ganoderma: insights into anticancer effects. Eur J Cancer Prev. 2016 Sep;25(5):462-71. doi: 10.1097/CEJ.0000000000000204. PMID: 26317382. https://pubmed.ncbi.nlm.nih.gov/26317382/ #reishi #lingzhi

Vetvicka V, Vetvickova J. Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts. Ann Transl Med. 2014 Feb;2(2):14. doi: 10.3978/j.issn.2305-5839.2014.01.05. PMID: 25332990; PMCID: PMC4202470.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202470/

Grienke U, Zöll M, Peintner U, Rollinger JM. European medicinal polypores–a modern view on traditional uses. J Ethnopharmacol. 2014 Jul 3;154(3):564-83. doi: 10.1016/j.jep.2014.04.030. Epub 2014 Apr 28. PMID: 24786572. https://pubmed.ncbi.nlm.nih.gov/24786572/ #Laetiporus sulphureus #Fomes fomentarius #Fomitopsis pinicola #Piptoporus betulinus #Laricifomes officinalis

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Plantes qui boostent les globules tueurs

Jiang Liu, Jing ZhangFengWangXing-fuChenChemical constituents from the buds of Lonicera macranthoides in Sichuan, China Biochemical Systematics and Ecology, ISSN: 0305-1978, Vol: 54, Page: 68-70 Publication Year2014 https://doi.org/10.1016/j.bse.2013.12.005
https://www.sciencedirect.com/science/article/pii/S030519781300238X?via%3Dihub

Emballement immunitaire ; cytokines

Olivier Montandrau sur Quora

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Plantes qui favorisent l’apoptose – suicide – des cellules malignes

Wang FF, Shi C, Yang Y, Fang Y, Sheng L, Li N. Medicinal mushroom Phellinus igniarius induced cell apoptosis in gastric cancer SGC-7901 through a mitochondria-dependent pathway. Biomed Pharmacother. 2018 Jun;102:18-25. doi: 10.1016/j.biopha.2018.03.038. Epub 2018 Mar 14. PMID: 29549725. https://pubmed.ncbi.nlm.nih.gov/29549725/

Safarzadeh E, Sandoghchian Shotorbani S, Baradaran B. Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull. 2014 Oct;4(Suppl 1):421-7. doi: 10.5681/apb.2014.062. Epub 2014 Aug 25. PMID: 25364657; PMCID: PMC4213780. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213780/

Lee BR, Lee JH, An HJ. Effects of Taraxacum officinale on fatigue and immunological parameters in mice. Molecules. 2012 Nov 7;17(11):13253-65. doi: 10.3390/molecules171113253. PMID: 23135630; PMCID: PMC6268574. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268574/ #pissenlit racine

Ovadje P, Chatterjee S, Griffin C, Tran C, Hamm C, Pandey S. Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract. J Ethnopharmacol. 2011 Jan 7;133(1):86-91. doi: 10.1016/j.jep.2010.09.005. Epub 2010 Sep 16. PMID: 20849941. https://pubmed.ncbi.nlm.nih.gov/20849941/ #pissenlit racine

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Nigelle

Majdalawieh AF, Fayyad MW. Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additive. J Ayurveda Integr Med. 2016 Jul-Sep;7(3):173-180. doi: 10.1016/j.jaim.2016.07.004. Epub 2016 Sep 17. PMID: 27649635; PMCID: PMC5052360. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052360/ #nigelle

Ahmad A, Rehman MU, Ahmad P, Alkharfy KM. Covid-19 and thymoquinone: Connecting the dots. Phytother Res. 2020 Nov;34(11):2786-2789. doi: 10.1002/ptr.6793. Epub 2020 Jul 10. PMID: 32588453; PMCID: PMC7361316. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361316/ #nigella #covid #nigelle

En anglais :

https://healthimpactnews.com/2014/black-seed-oil-cures-many-cancers-according-to-numerous-studies/

En cas de cancer : le cumin noir entraîne un accroissement de plus de 250 % des cellules de la moelle osseuse et une régression de 50 % de la croissance des cellules tumorales.

Khan MA, Chen HC, Tania M, Zhang DZ. Anticancer activities of Nigella sativa (black cumin). Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):226-32. doi: 10.4314/ajtcam.v8i5S.10. Epub 2011 Jul 3. PMID: 22754079; PMCID: PMC3252704. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252704/

Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. Thymoquinone and its therapeutic potentials. Pharmacol Res. 2015 May-Jun;95-96:138-58. doi: 10.1016/j.phrs.2015.03.011. Epub 2015 Mar 28. PMID: 25829334. https://pubmed.ncbi.nlm.nih.gov/25829334/ #nigella sativa #nigelle

Peng L, Liu A, Shen Y, Xu HZ, Yang SZ, Ying XZ, Liao W, Liu HX, Lin ZQ, Chen QY, Cheng SW, Shen WD. Antitumor and anti-angiogenesis effects of thymoquinone on osteosarcoma through the NF-κB pathway. Oncol Rep. 2013 Feb;29(2):571-8. doi: 10.3892/or.2012.2165. Epub 2012 Dec 4. PMID: 23232982. https://pubmed.ncbi.nlm.nih.gov/23232982/ #nigella sativa #nigelle

Gali-Muhtasib H, Ocker M, Kuester D, Krueger S, El-Hajj Z, Diestel A, Evert M, El-Najjar N, Peters B, Jurjus A, Roessner A, Schneider-Stock R. Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models. J Cell Mol Med. 2008 Jan-Feb;12(1):330-42. doi: 10.1111/j.1582-4934.2007.00095.x. PMID: 18366456; PMCID: PMC3823493. https://pubmed.ncbi.nlm.nih.gov/18366456/ #nigella sativa #nigelle

Ahmad, Aftab & Husain, Asif & Mujeeb, Mohd & Khan, Shah & Najmi, Abul & Siddiqui, Nasir & Damanhouri, Zoheir & Anwar, Firoz & Kishore, Kamal. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pacific journal of tropical biomedicine. 3. 337-52. 10.1016/S2221-1691(13)60075-1. https://www.researchgate.net/publication/236640180_A_review_on_therapeutic_potential_of_Nigella_sativa_A_miracle_herb

Al-Ali A, Alkhawajah AA, Randhawa MA, Shaikh NA. Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats. J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):25-7. PMID: 19385451. https://pubmed.ncbi.nlm.nih.gov/19385451/

Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res. 2003 Apr;17(4):299-305. doi: 10.1002/ptr.1309. PMID: 12722128. https://pubmed.ncbi.nlm.nih.gov/12722128/

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Armoise Artemisia

Akram Taleghani, Seyed Ahmad Emami, Zahra Tayarani-Najaran, Artemisia : a promising plant for the treatment of cancer, Bioorganic & Medicinal Chemistry, Volume 28, Issue 1, 2020, 115180, ISSN 0968-0896, https://doi.org/10.1016/j.bmc.2019.115180.
https://www.sciencedirect.com/science/article/pii/S0968089619308053 #artemisia vulgaris

Saleh AM, Aljada A, Rizvi SA, Nasr A, Alaskar AS, Williams JD. In vitro cytotoxicity of Artemisia vulgaris L. essential oil is mediated by a mitochondria-dependent apoptosis in HL-60 leukemic cell line. BMC Complement Altern Med. 2014 Jul 7;14:226. doi: 10.1186/1472-6882-14-226. PMID: 25002129; PMCID: PMC4227289.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227289/ #artemisia vulgaris

Sultan MH, Zuwaiel AA, Moni SS, Alshahrani S, Alqahtani SS, Madkhali O, Elmobark ME. Bioactive Principles and Potentiality of Hot Methanolic Extract of the Leaves from Artemisia absinthium L « in vitro Cytotoxicity Against Human MCF-7 Breast Cancer Cells, Antibacterial Study and Wound Healing Activity ». Curr Pharm Biotechnol. 2020;21(15):1711-1721. doi: 10.2174/1389201021666200928150519. PMID: 32988347. https://pubmed.ncbi.nlm.nih.gov/32988347/

&hecell

Huiles essentielles et cellules malignes

Suhail MM, Wu W, Cao A, Mondalek FG, Fung KM, Shih PT, Fang YT, Woolley C, Young G, Lin HK. Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells. BMC Complement Altern Med. 2011 Dec 15;11:129. doi: 10.1186/1472-6882-11-129. PMID: 22171782; PMCID: PMC3258268. #encens

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Plantes et cellules malignes – divers

C. Morissette, J. Goulet, R. Letarte, Effet d’une alimentation enrichie en ferments lactiques sur l’immunité humorale de la souris et sa survie à une dose létale de Klebsiella pneumoniae, Canadian Institute of Food Science and Technology Journal,
Volume 24, Issues 1–2, 1991, Pages 10-13, ISSN 0315-5463, https://doi.org/10.1016/S0315-5463(91)70012-6.
https://www.sciencedirect.com/science/article/pii/S0315546391700126

New tactic to stop the growth of a deadly brain cancer: The findings indicate the body may be the ultimate weapon against glioblastoma, but it needs help
https://www.sciencedaily.com/releases/2020/10/201027105359.htm d’après Kelly Johnston

Scientists have discovered a way to stop the growth of glioblastoma, the deadliest form of brain cancer. The finding provides a new tactic in the war against cancer that involves reprogramming the immune system to do what it does best – fight the tumor instead of fueling it.

War in the Blood, a film about treating cancer patients with CAR T cell therapy
https://www.uclh.nhs.uk/news/war-blood-film-about-treating-cancer-patients-car-t-cell-therapy

Pouillart PR. Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. Life Sci. 1998;63(20):1739-60. doi: 10.1016/s0024-3205(98)00279-3. PMID: 9820119.
https://pubmed.ncbi.nlm.nih.gov/9820119/

Mitsuoka, T., Hidaka, H. and Eida, T. (1987), Effect of fructo‐oligosaccharides on intestinal microflora. Nahrung, 31: 427-436. https://doi.org/10.1002/food.19870310528

Prévalence du cancer chez les personnes âgées et chez les centenaires
http://www.saging.com/articles/quelles-sont-les-principales-pathologies-observees-chez-les-centenaires-/key~clinique

Thomas ET, Del Mar C, Glasziou P, Wright G, Barratt A, Bell KJL. Prevalence of incidental breast cancer and precursor lesions in autopsy studies: a systematic review and meta-analysis. BMC Cancer. 2017 Dec 2;17(1):808. doi: 10.1186/s12885-017-3808-1. PMID: 29197354; PMCID: PMC5712106.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712106/

Dominique Dupagne La controverse sur la mammographie de dépistage s’amplifie #dormantes
https://www.franceinter.fr/emissions/sante-polemique/sante-polemique-14-decembre-2017

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Général

Edris AE. Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res. 2007 Apr;21(4):308-23. doi: 10.1002/ptr.2072. PMID: 17199238. https://pubmed.ncbi.nlm.nih.gov/17199238/ #general

Sordo-Bahamonde, Christian; Vitale, Massimo; Lorenzo-Herrero, Seila; López-Soto, Alejandro; Gonzalez, Segundo. 2020. « Mechanisms of Resistance to NK Cell Immunotherapy » Cancers 12, no. 4: 893. https://doi.org/10.3390/cancers12040893
https://www.mdpi.com/2072-6694/12/4/893

Park CR, Lee JS, Son CG, Lee NH. A survey of herbal medicines as tumor microenvironment-modulating agents. Phytother Res. 2021 Jan;35(1):78-94. doi: 10.1002/ptr.6784. Epub 2020 Jul 13. PMID: 32658314. https://pubmed.ncbi.nlm.nih.gov/32658314/ #stroma #microenvironnement de la tumeur

Pal D, Mitra AK. MDR- and CYP3A4-mediated drug-herbal interactions. Life Sci. 2006 Mar 27;78(18):2131-45. doi: 10.1016/j.lfs.2005.12.010. Epub 2006 Jan 25. PMID: 16442130. https://pubmed.ncbi.nlm.nih.gov/16442130/ hypericin, kaempferol, quercetin and silibinin 

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Ayur vedic, tibetan, chinese medicines

Hassannia B, Logie E, Vandenabeele P, Vanden Berghe T, Vanden Berghe W. Withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug. Biochem Pharmacol. 2020 Mar;173:113602. doi: 10.1016/j.bcp.2019.08.004. Epub 2019 Aug 9. PMID: 31404528. https://pubmed.ncbi.nlm.nih.gov/31404528/ #Withania somnifera #Ashwagandha

Tang C, Zhao CC, Yi H, Geng ZJ, Wu XY, Zhang Y, Liu Y, Fan G. Traditional Tibetan Medicine in Cancer Therapy by Targeting Apoptosis Pathways. Front Pharmacol. 2020 Jul 7;11:976. doi: 10.3389/fphar.2020.00976. PMID: 32774302; PMCID: PMC7381342. https://pubmed.ncbi.nlm.nih.gov/32774302/ #Ophiocordyceps sinensis #Phyllanthus emblica #Rhodiola kirilowii

Luo, H., Vong, C.T., Chen, H. et al. Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine. Chin Med 14, 48 (2019). https://doi.org/10.1186/s13020-019-0270-9 https://rdcu.be/cfazV identique au lien suivant https://link.springer.com/epdf/10.1186/s13020-019-0270-9

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Graviola

Acétogénines et cancer (Graviola)
https://fr.sanus-q.com/blogs/news/acetogenins-and-cancer-graviola

  1. Paul, Jeno; Gnanam, R.; M. Jayadeepa, R.; Arul, L. Anti Cancer Activity on Graviola, an Exciting Medicinal Plant Extract vs Various Cancer Cell Lines and a Detailed Computational Study on its Potent Anti-Cancerous Leads. Current Topics in Medicinal Chemistry. Volume 13, Number 14, July 2013, pp. 1666-1673(8) #graviola #annona muricata
  2. Torres MP, Rachagani S, Purohit V, et al. Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism. Cancer Letters. Oct 1 2012;323(1):29-40. doi: 10 #graviola #annona muricata
  3. Dai and Hogan, et al. Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression. Nutrition and Cancer. 2011; 63(5):795-801. #graviola #annona muricata
  4. Yang C, Gundala SR, Mukkavilli R, Vangala S, Reid MD, Aneja R. Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer. Carcinogenesis. 2015 Jun;36(6):656-65. doi: 10.1093/carcin/bgv046. Epub 2015 Apr 11. #graviola #annona muricata
  5. Han et al. Annonaceous acetogenin mimic AA005 induces cancer cell death via apoptosis inducing factor through a caspase-3-independent mechanism. BMC Cancer. March 2015 #graviola #annona muricata #corossolier

Solanum, swertia, cichorium, smilax, etc.

Lai YJ, Tai CJ, Wang CW, Choong CY, Lee BH, Shi YC, Tai CJ. Anti-Cancer Activity of Solanum nigrum (AESN) through Suppression of Mitochondrial Function and Epithelial-Mesenchymal Transition (EMT) in Breast Cancer Cells. Molecules. 2016 Apr 28;21(5):553. doi: 10.3390/molecules21050553. PMID: 27136519; PMCID: PMC6274361.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274361/ #morelle noire

Gabrani R, Jain R, Sharma A, Sarethy IP, Dang S, Gupta S. Antiproliferative Effect of Solanum nigrum on Human Leukemic Cell Lines. Indian J Pharm Sci. 2012 Sep;74(5):451-3. doi: 10.4103/0250-474X.108421. PMID: 23716874; PMCID: PMC3660872. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660872/ #morelle noire

Saha P, Das S. Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata. Asian Pac J Cancer Prev. 2010;11(6):1445-9. PMID: 21338178. https://pubmed.ncbi.nlm.nih.gov/21338178/ #swertia chirata #chirayita #chirayata

Promising Phytochemicals from Indian Medicinal Plants Dr. Amrit Pal Singh MD (Alternative Medicine), Medical Executive, Ind-Swift Ltd, Chandigarh (India) 9 pages

https://www.jstage.jst.go.jp/article/bpb1993/23/8/23_8_1005/_pdf #cichorium intybus

Hu LL, Chen DS, Wang YY, Qin Y, Huang P, Yu LX, Liao J, Hua XL. Smilax china L. rhizome extract inhibits nuclear factor-κB and induces apoptosis in ovarian cancer cells. Chin J Integr Med. 2015 Dec;21(12):907-15. doi: 10.1007/s11655-014-1788-9. Epub 2014 Dec 16. PMID: 25511428. https://pubmed.ncbi.nlm.nih.gov/25511428/ #salsepareille

Yuan-Li Li, Guo-Ping Gan, Hui-Zhan Zhang, He-Zhen Wu, Chang-Long Li, Yong-Ping Huang, Yan-Wen Liu, Jian-Wen Liu, A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines,
Journal of Ethnopharmacology, Volume 113, Issue 1, 2007, Pages 115-124, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2007.05.016.
https://www.sciencedirect.com/science/article/pii/S0378874107002486 #smilax china

Greenwell M, Rahman PK. Medicinal Plants: Their Use in Anticancer Treatment. Int J Pharm Sci Res. 2015 Oct 1;6(10):4103-4112. doi: 10.13040/IJPSR.0975-8232.6(10).4103-12. PMID: 26594645; PMCID: PMC4650206.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650206/ 1 #Taxus brevifolia = #If de l’ouest 2 #Podophyllum peltatum = #podophylle pelté 3 #Catharanthus roseus = #Pervenche de Madagascar 4 #Maclura pomifera = #Oranger des Osages 5 #Derris Malaccensis 6 #thé vert 7 #Combretum caffrum 8 #Raphanus sativus = #radis 9 #Dysoxylum binectariferum 10 #Papaver somniferum = #Pavot somnifère 11 #brassica (famille des choux)

Afrin F, Chi M, Eamens AL, Duchatel RJ, Douglas AM, Schneider J, Gedye C, Woldu AS, Dun MD. Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer. Cancers (Basel). 2020 Apr 23;12(4):1033. doi: 10.3390/cancers12041033. PMID: 32340151; PMCID: PMC7226605. https://pubmed.ncbi.nlm.nih.gov/32340151/

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Papaye

Pandey S, Cabot PJ, Shaw PN, Hewavitharana AK. Anti-inflammatory and immunomodulatory properties of Carica papaya. J Immunotoxicol. 2016 Jul;13(4):590-602. doi: 10.3109/1547691X.2016.1149528. Epub 2016 Jul 14. PMID: 27416522. https://pubmed.ncbi.nlm.nih.gov/27416522/

Santana LF, Inada AC, Espirito Santo BLSD, Filiú WFO, Pott A, Alves FM, Guimarães RCA, Freitas KC, Hiane PA. Nutraceutical Potential of Carica papaya in Metabolic Syndrome. Nutrients. 2019 Jul 16;11(7):1608. doi: 10.3390/nu11071608. PMID: 31315213; PMCID: PMC6682863. https://pubmed.ncbi.nlm.nih.gov/31315213/

Nguyen TT, Shaw PN, Parat MO, Hewavitharana AK. Anticancer activity of Carica papaya: a review. Mol Nutr Food Res. 2013 Jan;57(1):153-64. doi: 10.1002/mnfr.201200388. Epub 2012 Dec 5. PMID: 23212988. https://pubmed.ncbi.nlm.nih.gov/23212988/

Ahlawat J, Kumar V, Gopinath P. Carica papaya loaded poly (vinyl alcohol)-gelatin nanofibrous scaffold for potential application in wound dressing. Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109834. doi: 10.1016/j.msec.2019.109834. Epub 2019 May 30. PMID: 31349516. https://pubmed.ncbi.nlm.nih.gov/31349516/ #blessures

Q10, garlic, aloe, ginseng, uncaria, grenade, calendula

Garrido-Maraver J, Cordero MD, Oropesa-Avila M, Vega AF, de la Mata M, Pavon AD, Alcocer-Gomez E, Calero CP, Paz MV, Alanis M, de Lavera I, Cotan D, Sanchez-Alcazar JA. Clinical applications of coenzyme Q10. Front Biosci (Landmark Ed). 2014 Jan 1;19:619-33. doi: 10.2741/4231. PMID: 24389208. https://pubmed.ncbi.nlm.nih.gov/24389208/ #ubiquinone

Savini I, Rossi A, Catani MV, Ceci R, Avigliano L. Redox regulation of vitamin C transporter SVCT2 in C2C12 myotubes. Biochem Biophys Res Commun. 2007 Sep 21;361(2):385-90. doi: 10.1016/j.bbrc.2007.07.007. Epub 2007 Jul 16. PMID: 17643393. https://pubmed.ncbi.nlm.nih.gov/17643393/ #lipoate #oxydoreduction #gene

Thomson M, Ali M. Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Curr Cancer Drug Targets. 2003 Feb;3(1):67-81. doi: 10.2174/1568009033333736. PMID: 12570662. https://pubmed.ncbi.nlm.nih.gov/12570662/ #ail #revue

Natacha Michayewicz L’Aloe vera, plante médicinale traditionnellement et largement utilisée depuis des millénaires, aux nombreuses propriétés thérapeutiques. Plante miracle ? https://hal.univ-lorraine.fr/hal-01731937/document

Gao Y, Kuok KI, Jin Y, Wang R. Biomedical applications of Aloe vera. Crit Rev Food Sci Nutr. 2019;59(sup1):S244-S256. doi: 10.1080/10408398.2018.1496320. Epub 2018 Sep 13. PMID: 29999415. https://pubmed.ncbi.nlm.nih.gov/29999415/

Shergis JL, Zhang AL, Zhou W, Xue CC. Panax ginseng in randomised controlled trials: a systematic review. Phytother Res. 2013 Jul;27(7):949-65. doi: 10.1002/ptr.4832. Epub 2012 Sep 12. PMID: 22969004. https://pubmed.ncbi.nlm.nih.gov/22969004/

Della Valle V. Uncaria tomentosa. G Ital Dermatol Venereol. 2017 Dec;152(6):651-657. doi: 10.23736/S0392-0488.17.05712-1. PMID: 29050447. https://pubmed.ncbi.nlm.nih.gov/29050447/

Sharma P, McClees SF, Afaq F. Pomegranate for Prevention and Treatment of Cancer: An Update. Molecules. 2017 Jan 24;22(1):177. doi: 10.3390/molecules22010177. PMID: 28125044; PMCID: PMC5560105. https://pubmed.ncbi.nlm.nih.gov/28125044/ #grenade #Punica granatum

Cruceriu D, Balacescu O, Rakosy E. Calendula officinalis: Potential Roles in Cancer Treatment and Palliative Care. Integr Cancer Ther. 2018 Dec;17(4):1068-1078. doi: 10.1177/1534735418803766. Epub 2018 Oct 5. PMID: 30289008; PMCID: PMC6247547. https://pubmed.ncbi.nlm.nih.gov/30289008/

Emblica, tea, neurolaena, curcuma, polygonum, spirulina,

Baliga MS, Dsouza JJ. Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer. Eur J Cancer Prev. 2011 May;20(3):225-39. doi: 10.1097/CEJ.0b013e32834473f4. PMID: 21317655. https://pubmed.ncbi.nlm.nih.gov/21317655/ #Phyllanthus emblica

Yang CS, Chen G, Wu Q. Recent scientific studies of a traditional chinese medicine, tea, on prevention of chronic diseases. J Tradit Complement Med. 2014 Jan;4(1):17-23. doi: 10.4103/2225-4110.124326. PMID: 24872929; PMCID: PMC4032838. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032838/ #thé vert #green tea

Lajter I, Vasas A, Béni Z, Forgo P, Binder M, Bochkov V, Zupkó I, Krupitza G, Frisch R, Kopp B, Hohmann J. Sesquiterpenes from Neurolaena lobata and their antiproliferative and anti-inflammatory activities. J Nat Prod. 2014 Mar 28;77(3):576-82. doi: 10.1021/np400834c. Epub 2014 Jan 29. PMID: 24476550; PMCID: PMC3971758. https://pubmed.ncbi.nlm.nih.gov/24476550/ #antiproliferatif

Mishra S, Verma SS, Rai V, Awasthee N, Arya JS, Maiti KK, Gupta SC. Curcuma raktakanda Induces Apoptosis and Suppresses Migration in Cancer Cells: Role of Reactive Oxygen Species. Biomolecules. 2019 Apr 23;9(4):159. doi: 10.3390/biom9040159. PMID: 31018580; PMCID: PMC6523773. https://pubmed.ncbi.nlm.nih.gov/31018580/

Wu X, Li Q, Feng Y, Ji Q. Antitumor Research of the Active Ingredients from Traditional Chinese Medical Plant Polygonum Cuspidatum. Evid Based Complement Alternat Med. 2018 Nov 21;2018:2313021. doi: 10.1155/2018/2313021. PMID: 30584449; PMCID: PMC6280292. https://pubmed.ncbi.nlm.nih.gov/30584449/ #resveratrol

Mahmoud YI, Shehata AMM, Fares NH, Mahmoud AA. Spirulina inhibits hepatocellular carcinoma through activating p53 and apoptosis and suppressing oxidative stress and angiogenesis. Life Sci. 2021 Jan 15;265:118827. doi: 10.1016/j.lfs.2020.118827. Epub 2020 Nov 28. PMID: 33253720. https://pubmed.ncbi.nlm.nih.gov/33253720/ #apoptose #angiogenèse

Berries, cranberries, blueberry, ligonberry,

Weh KM, Clarke J, Kresty LA. Cranberries and Cancer: An Update of Preclinical Studies Evaluating the Cancer Inhibitory Potential of Cranberry and Cranberry Derived Constituents. Antioxidants (Basel). 2016 Aug 18;5(3):27. doi: 10.3390/antiox5030027. PMID: 27548236; PMCID: PMC5039576. https://pubmed.ncbi.nlm.nih.gov/27548236/ #canneberge

Davidson KT, Zhu Z, Balabanov D, Zhao L, Wakefield MR, Bai Q, Fang Y. Beyond Conventional Medicine – a Look at Blueberry, a Cancer-Fighting Superfruit. Pathol Oncol Res. 2018 Oct;24(4):733-738. doi: 10.1007/s12253-017-0376-2. Epub 2017 Dec 28. PMID: 29285736. https://pubmed.ncbi.nlm.nih.gov/29285736/ #myrtille

Hoornstra D, Vesterlin J, Pärnänen P, Al-Samadi A, Zlotogorski-Hurvitz A, Vered M, Salo T. Fermented Lingonberry Juice Inhibits Oral Tongue Squamous Cell Carcinoma Invasion In Vitro Similarly to Curcumin. In Vivo. 2018 Sep-Oct;32(5):1089-1095. doi: 10.21873/invivo.11350. PMID: 30150430; PMCID: PMC6199607. https://pubmed.ncbi.nlm.nih.gov/?term=lingonberry+cancer #airelle

Garlic, allium, avocado, cocoa, algae, barley-orge, alfalfa, mollusques, oeufs, polen, chardon marie, avoine

Nicastro HL, Ross SA, Milner JA. Garlic and onions: their cancer prevention properties. Cancer Prev Res (Phila). 2015 Mar;8(3):181-9. doi: 10.1158/1940-6207.CAPR-14-0172. Epub 2015 Jan 13. PMID: 25586902; PMCID: PMC4366009. https://pubmed.ncbi.nlm.nih.gov/25586902/ #ail #allium #oignon #échalote #poireau #ciboulette

Lu QY, Arteaga JR, Zhang Q, Huerta S, Go VL, Heber D. Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances. J Nutr Biochem. 2005 Jan;16(1):23-30. doi: 10.1016/j.jnutbio.2004.08.003. PMID: 15629237. https://pubmed.ncbi.nlm.nih.gov/15629237/ #avocat

Zamanian-Azodi M, Rezaei-Tavirani M. Investigation of health benefits of cocoa in human colorectal cancer cell line, HT-29 through interactome analysis. Gastroenterol Hepatol Bed Bench. 2019 Winter;12(1):67-73. PMID: 30949322; PMCID: PMC6441487. https://pubmed.ncbi.nlm.nih.gov/30949322/ #cacao

Kim SK, Karagozlu MZ. Marine algae: natural product source for gastrointestinal cancer treatment. Adv Food Nutr Res. 2011;64:225-33. doi: 10.1016/B978-0-12-387669-0.00017-X. PMID: 22054950. https://pubmed.ncbi.nlm.nih.gov/22054950/ #algues

Wan-Loy C, Siew-Moi P. Marine Algae as a Potential Source for Anti-Obesity Agents. Mar Drugs. 2016 Dec 7;14(12):222. doi: 10.3390/md14120222. PMID: 27941599; PMCID: PMC5192459. https://pubmed.ncbi.nlm.nih.gov/27941599/ #algues #coupe faim #satiété

Kawka K, Lemieszek MK, Rzeski W. Chemopreventive properties of young green barley extracts in in vitro model of colon cancer. Ann Agric Environ Med. 2019 Mar 22;26(1):174-181. doi: 10.26444/aaem/102624. Epub 2019 Feb 13. PMID: 30922050. https://pubmed.ncbi.nlm.nih.gov/30922050/ #jeune orge vert

Gatouillat G, Magid AA, Bertin E, Okiemy-Akeli MG, Morjani H, Lavaud C, Madoulet C. Cytotoxicity and apoptosis induced by alfalfa (Medicago sativa) leaf extracts in sensitive and multidrug-resistant tumor cells. Nutr Cancer. 2014;66(3):483-91. doi: 10.1080/01635581.2014.884228. Epub 2014 Mar 14. PMID: 24628411. https://pubmed.ncbi.nlm.nih.gov/24628411/ #luzerne

Correia-da-Silva M, Sousa E, Pinto MMM, Kijjoa A. Anticancer and cancer preventive compounds from edible marine organisms. Semin Cancer Biol. 2017 Oct;46:55-64. doi: 10.1016/j.semcancer.2017.03.011. Epub 2017 Apr 7. PMID: 28392464. https://pubmed.ncbi.nlm.nih.gov/28392464/ #mollusques

Rodríguez-Rodríguez E, Aparicio Vizuete A, Sánchez-Rodríguez P, Lorenzo Mora AM, López-Sobaler AM, Ortega RM. Deficiencia en vitamina D de la población española. Importancia del huevo en la mejora nutricional [Vitamin D deficiency in Spanish population. Importance of egg on nutritional improvement]. Nutr Hosp. 2019 Aug 27;36(Spec No3):3-7. Spanish. doi: 10.20960/nh.02798. PMID: 31368328. https://pubmed.ncbi.nlm.nih.gov/31368328/ #Oeufs #VitD

Denisow B, Denisow-Pietrzyk M. Biological and therapeutic properties of bee pollen: a review. J Sci Food Agric. 2016 Oct;96(13):4303-9. doi: 10.1002/jsfa.7729. Epub 2016 Apr 19. PMID: 27013064. https://pubmed.ncbi.nlm.nih.gov/27013064/

Kroll DJ, Shaw HS, Oberlies NH. Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies. Integr Cancer Ther. 2007 Jun;6(2):110-9. doi: 10.1177/1534735407301825. PMID: 17548790. https://pubmed.ncbi.nlm.nih.gov/17548790/ #chardon marie

Turrini E, Maffei F, Milelli A, Calcabrini C, Fimognari C. Overview of the Anticancer Profile of Avenanthramides from Oat. Int J Mol Sci. 2019 Sep 13;20(18):4536. doi: 10.3390/ijms20184536. PMID: 31540249; PMCID: PMC6770293. https://pubmed.ncbi.nlm.nih.gov/31540249/ #Avoine

Sophora, cannelle, girofle, thym, sauge, lavande, romarin, rue

Wang R, Deng X, Gao Q, Wu X, Han L, Gao X, Zhao S, Chen W, Zhou R, Li Z, Bai C. Sophora alopecuroides L.: An ethnopharmacological, phytochemical, and pharmacological review. J Ethnopharmacol. 2020 Feb 10;248:112172. doi: 10.1016/j.jep.2019.112172. Epub 2019 Aug 20. PMID: 31442619. https://pubmed.ncbi.nlm.nih.gov/31442619/

Ishrat Husain, Rumana Ahmad, Anu Chandra, Syed Tasleem Raza, Yogeshwer Shukla, Farzana Mahdi,
Phytochemical characterization and biological activity evaluation of ethanolic extract of Cinnamomum zeylanicum,
Journal of Ethnopharmacology, Volume 219, 2018, Pages 110-116, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2018.02.001.
https://www.sciencedirect.com/science/article/pii/S0378874117330076 #cannelle

Das A, K H, S K DK, K HR, Jayaprakash B. Evaluation of Therapeutic Potential of Eugenol-A Natural Derivative of Syzygium aromaticum on Cervical Cancer. Asian Pac J Cancer Prev. 2018 Jul 27;19(7):1977-1985. doi: 10.22034/APJCP.2018.19.7.1977. PMID: 30051686; PMCID: PMC6165650. https://pubmed.ncbi.nlm.nih.gov/30051686/ #girofle #Eugenia caryophyllus

Kubatka P, Uramova S, Kello M, Kajo K, Samec M, Jasek K, Vybohova D, Liskova A, Mojzis J, Adamkov M, Zubor P, Smejkal K, Svajdlenka E, Solar P, Samuel SM, Zulli A, Kassayova M, Lasabova Z, Kwon TK, Pec M, Danko J, Büsselberg D. Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro. Int J Mol Sci. 2019 Apr 9;20(7):1749. doi: 10.3390/ijms20071749. PMID: 30970626; PMCID: PMC6479806. https://pubmed.ncbi.nlm.nih.gov/30970626/ #thym

Rózalski M, Kuźma L, Krajewska U, Wysokińska H. Cytotoxic and proapoptotic activity of diterpenoids from in vitro cultivated Salvia sclarea roots. Studies on the leukemia cell lines. Z Naturforsch C J Biosci. 2006 Jul-Aug;61(7-8):483-8. doi: 10.1515/znc-2006-7-804. PMID: 16989306. https://pubmed.ncbi.nlm.nih.gov/16989306/ Sauge sclarée

Zhao Y, Chen R, Wang Y, Qing C, Wang W, Yang Y. In Vitro and In Vivo Efficacy Studies of Lavender angustifolia Essential Oil and Its Active Constituents on the Proliferation of Human Prostate Cancer. Integr Cancer Ther. 2017 Jun;16(2):215-226. doi: 10.1177/1534735416645408. Epub 2016 May 5. PMID: 27151584; PMCID: PMC5739122. https://pubmed.ncbi.nlm.nih.gov/27151584/ #Lavandula angustifolia

Moore J, Yousef M, Tsiani E. Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols. Nutrients. 2016 Nov 17;8(11):731. doi: 10.3390/nu8110731. PMID: 27869665; PMCID: PMC5133115. https://pubmed.ncbi.nlm.nih.gov/27869665/ #romarin #rosmarinus officinalis LIBRE

Fadlalla K, Watson A, Yehualaeshet T, Turner T, Samuel T. Ruta graveolens extract induces DNA damage pathways and blocks Akt activation to inhibit cancer cell proliferation and survival. Anticancer Res. 2011 Jan;31(1):233-41. PMID: 21273604; PMCID: PMC3124362. https://pubmed.ncbi.nlm.nih.gov/21273604/ #rue des jardins LIBRE

Camphor, arctium-bardane, rheum-rhubarbe, DMSO, carvacol, muscade, urtica

Moayedi Y, Greenberg SA, Jenkins BA, Marshall KL, Dimitrov LV, Nelson AM, Owens DM, Lumpkin EA. Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms. Mol Carcinog. 2019 May;58(5):722-734. doi: 10.1002/mc.22965. Epub 2019 Jan 20. PMID: 30582219; PMCID: PMC6724528. https://pubmed.ncbi.nlm.nih.gov/30582219/ #camphre

Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011 Oct;19(5):245-54. doi: 10.1007/s10787-010-0062-4. Epub 2010 Oct 28. PMID: 20981575. https://pubmed.ncbi.nlm.nih.gov/20981575/ #bardane #essiac

Zhang Q, Liu J, Li R, Zhao R, Zhang M, Wei S, Ran D, Jin W, Wu C. A Network Pharmacology Approach to Investigate the Anticancer Mechanism and Potential Active Ingredients of Rheum palmatum L. Against Lung Cancer via Induction of Apoptosis. Front Pharmacol. 2020 Nov 4;11:528308. doi: 10.3389/fphar.2020.528308. PMID: 33250766; PMCID: PMC7672213. https://pubmed.ncbi.nlm.nih.gov/33250766/ #rhubarbe

Hammoudeh SM, Hammoudeh AM, Hamoudi R. High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay. Histochem Cell Biol. 2019 Jul;152(1):75-84. doi: 10.1007/s00418-019-01775-7. Epub 2019 Feb 16. PMID: 30778673; PMCID: PMC6620243. https://pubmed.ncbi.nlm.nih.gov/30778673/

Suntres ZE, Coccimiglio J, Alipour M. The bioactivity and toxicological actions of carvacrol. Crit Rev Food Sci Nutr. 2015;55(3):304-18. doi: 10.1080/10408398.2011.653458. PMID: 24915411. https://pubmed.ncbi.nlm.nih.gov/24915411/

Kim EY, Choi HJ, Park MJ, Jung YS, Lee SO, Kim KJ, Choi JH, Chung TW, Ha KT. Myristica fragrans Suppresses Tumor Growth and Metabolism by Inhibiting Lactate Dehydrogenase A. Am J Chin Med. 2016;44(5):1063-79. doi: 10.1142/S0192415X16500592. Epub 2016 Jul 19. PMID: 27430914. https://pubmed.ncbi.nlm.nih.gov/27430914/ #muscade #antiprolifération

Esposito S, Bianco A, Russo R, Di Maro A, Isernia C, Pedone PV. Therapeutic Perspectives of Molecules from Urtica dioica Extracts for Cancer Treatment. Molecules. 2019 Jul 29;24(15):2753. doi: 10.3390/molecules24152753. PMID: 31362429; PMCID: PMC6695697. https://pubmed.ncbi.nlm.nih.gov/31362429/ #ortie

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Clay, zeolite

Phillips TD. Dietary clay in the chemoprevention of aflatoxin-induced disease. Toxicol Sci. 1999 Dec;52(2 Suppl):118-26. doi: 10.1093/toxsci/52.suppl_1.118. PMID: 10630600. https://pubmed.ncbi.nlm.nih.gov/10630600/ #zeolite #argile

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Cas cliniques cellules malignes

Sagar SM, Yance D, Wong RK. Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. Curr Oncol. 2006 Feb;13(1):14-26. PMID: 17576437; PMCID: PMC1891166. https://pubmed.ncbi.nlm.nih.gov/17576437/

Voici cinq des cas rapportés :

1. Patient D.A. a 47 year-old mechanic who presented with a 4.5 cm. Non-Hodgkin’s lymphoma on the right side of his head, with gaping incision from a recent biopsy, and tremendous inflammatory erythema. Artesunate, 60mg was administered IM 14 consecutive days and he switched diets to high protein/vegetable (Kelley parasympathetic type diet). At the end of two weeks, a depression appeared at the apex of the tumor. Four weeks later, the mass was completely gone, skull surface smooth, incision totally healed and erythema virtually cleared. Apparently cancer-free as of this writing 6 months later. #Artemisia

2. Patient V.M. an 83 year old Toronto resident. Healthy most of her life, she now had a non-small cell lung carcinoma in the right lower lobe, considered non-resectable because of heart failure and circulatory problems. She received Artemisinin 500mg BID from Allergy Research Group and Carnivora oral, via nebulizer, 5cc BID. In 4 months the tumor shrunk to 1×2 cm and her oncologist felt this represented scar tissue and declared her cancer free. (Her heart condition improved considerably with Co Enzyme Q10, 600mg daily). #Artemisia

3. Patient D.E., a 47 year-old Alaska resident with stage 4 breast cancer and metastases to T1 with significant pain, vertebral collapse and local neurological impairment. First seen May 2001, she received a series of IPT (insulin potentiation therapy-low dose chemotherapy), high dose vitamin C infusions, supplements, and dendritic cell vaccine, dietary management (Kelly sympathetic type diet), and detoxification strategies. Most symptoms had cleared within 4 months (October 2001). In January 2002, she received artesunate IV (source: mainland China), plus oral artemisinin 300 mg BID (ARG and Wellcare Pharma) which has been continued. Six months later she was happy to report she has no symptoms whatsoever and is living a normal life. Her local provider believes the regressed mass is now scar tissue. #Artemisia

4. Patient F.A., an 81 year-old Californian with multiple skin cancers including one active recurrent quarter-sized lesion that had been burned 4 times previously. Topical artemisinin (one capsule ARG artemisinin in 50% DMSO) applied twice daily caused the large lesion to fall off within 5 days and other smaller skin cancers to regress. His wife reported the same with her skin cancers. #Artemisia

5. L.L. is a West Coast woman in her 40’s with breast cancer and extremely painful metastasis all over her spine. She had received limited radiation therapy to reduce the pain in the thoracic spine prior to consulting me. She began artemisinin, and a variety of complementary strategies, including diet, detoxification and Kelly type proteolytic enzymes (from Allergy Research Group). Immediately, her energy exploded. Her pain level took a dive when she received treatment from an Edgar Cayce Foundation healer. Her comment after two weeks on artemisinin was “Last week I thought I was dying, and today for the first time in months, I believe I am going to live.” Four months into therapy using oral supplements alone (no IV therapy), diet and detoxification strategies, a PET scan, the most efficient and sensitive study for spread of cancer, did not show any activity anywhere in her spine, even in places that were present before and not radiated! Further, the scan did not confirm definite cancer activity anywhere else! #Artemisia
In Rowen R. J. Artemisinin: From Malaria to Cancer Treatment https://www.townsendletter.com/Dec2002/artemisinin1202.htm

Lauréat le Prix de précurseur: Le Dr Stephen Sagar

La prise de décision

Balneaves LG, Weeks L, Seely D. Patient decision-making about complementary and alternative medicine in cancer management: context and process. Curr Oncol. 2008 Aug;15 Suppl 2(Suppl 2):s94-s100. doi: 10.3747/co.v15i0.280. PMID: 18769576; PMCID: PMC2528558. https://pubmed.ncbi.nlm.nih.gov/18769576/

Résistance à la chimiothérapie

Régina A, Demeule M, Laplante A, Jodoin J, Dagenais C, Berthelet F, Moghrabi A, Béliveau R. Multidrug resistance in brain tumors: roles of the blood-brain barrier. Cancer Metastasis Rev. 2001;20(1-2):13-25. doi: 10.1023/a:1013104423154. PMID: 11831641. https://pubmed.ncbi.nlm.nih.gov/11831641/

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Hypnose, transe, etc

Dominique Meggle Hypnose profonde Courte vidéo

Dominique Meggle Troisième séance d’hypnose avec Vincent dans le cadre d’un stage de formation à la pratique de l’hypnose ericksonienne 18 minutes

BLACK S, HUMPHREY JH, NIVEN JS. Inhibition of Mantoux reaction by direct suggestion under hypnosis. Br Med J. 1963 Jun 22;1(5346):1649-52. doi: 10.1136/bmj.1.5346.1642-b. PMID: 13971374; PMCID: PMC2124383. https://pubmed.ncbi.nlm.nih.gov/13971374/ #cuti réaction

Hypnosis in Contemporary Medicine JAMES H. STEWART, MD https://www.mayoclinicproceedings.org/article/S0025-6196(11)63203-5/pdf

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Jeûne

Yuan CL, Sharma N, Gilge DA, Stanley WC, Li Y, Hatzoglou M, Previs SF. Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E216-22. doi: 10.1152/ajpendo.00545.2007. Epub 2008 Apr 29. PMID: 18445754; PMCID: PMC2493593. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493593/ #jeûne

Iso T., Kurabayashi M. (2017) Fatty Acid Uptake by the Heart During Fasting. In: Preedy V., Patel V. (eds) Handbook of Famine, Starvation, and Nutrient Deprivation. Springer, Cham. https://doi.org/10.1007/978-3-319-40007-5_13-1 https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-40007-5_13-1 #jeûne

Bradley RM, Mardian EB, Moes KA, Duncan RE. Acute Fasting Induces Expression of Acylglycerophosphate Acyltransferase (AGPAT) Enzymes in Murine Liver, Heart, and Brain. Lipids. 2017 May;52(5):457-461. doi: 10.1007/s11745-017-4251-4. Epub 2017 Apr 12. PMID: 28405875. https://pubmed.ncbi.nlm.nih.gov/28405875/ #jeûne

Feillet CA, Albrecht U, Challet E. « Feeding time » for the brain: a matter of clocks. J Physiol Paris. 2006 Nov-Dec;100(5-6):252-60. doi: 10.1016/j.jphysparis.2007.05.002. Epub 2007 Jun 7. PMID: 17629684. https://pubmed.ncbi.nlm.nih.gov/17629684/ #jeûne #rythme circadien #horloge cérébrale

Antunes F, Erustes AG, Costa AJ, Nascimento AC, Bincoletto C, Ureshino RP, Pereira GJS, Smaili SS. Autophagy and intermittent fasting: the connection for cancer therapy? Clinics (Sao Paulo). 2018 Dec 10;73(suppl 1):e814s. doi: 10.6061/clinics/2018/e814s. PMID: 30540126; PMCID: PMC6257056. https://pubmed.ncbi.nlm.nih.gov/30540126/ #autophagie #jeûne

Bagherniya M, Butler AE, Barreto GE, Sahebkar A. The effect of fasting or calorie restriction on autophagy induction: A review of the literature. Ageing Res Rev. 2018 Nov;47:183-197. doi: 10.1016/j.arr.2018.08.004. Epub 2018 Aug 30. PMID: 30172870. https://pubmed.ncbi.nlm.nih.gov/30172870/ #jeûne #autophagie

Jérôme Lemar. L’appellation ”jeûne thérapeutique” est-elle fondée ou usurpée ? : éléments de réponse
d’après une revue de bibliographie chez l’animal et chez l’homme. Médecine humaine et pathologie. https://dumas.ccsd.cnrs.fr/dumas-00651422/document THÈSE PRÉSENTÉE POUR L’OBTENTION DU DOCTORAT EN MÉDECINE DIPLÔME D’ÉTAT 2011

Juliette Gueguen, Isabelle Dufaure, Caroline Barry, Bruno Falissard Evaluation de l’efficacité de la pratique du jeûne comme pratique à visée préventive ou thérapeutique Inserm Rapport thématique Avec l’expertise critique d’Hadrien Reyre et de Luca Semerano 10/01/2014

Le Docteur Michel Cymes tire sur le jeûne :

https://tvmag.lefigaro.fr/programme-tv/michel-cymes-nous-tordons-le-cou-a-la-monodiete-et-au-jeune_1ea7bea0-cd81-11e9-b6e2-1cb83f343889/

https://www.rtl.fr/actu/bien-etre/cancer-michel-cymes-met-en-garde-contre-les-effets-du-jeune-7800936319

Le Professeur Claude Pichard devrait être poursuivi en justice.
En effet il a prêté le Serment d’Hippocrate et s’est engagé à dire le vrai à son patient.
Ce qu’il dit sur le jeûne est un tissus de mensonges démentis par les recherches académiques !!!
https://pulsations.hug.ch/article/le-jeune-une-fausse-bonne-idee

Et les perles de quelques médecins français qui n’ont pas lu beaucoup de publications académiques – voire aucune :
https://www.lemonde.fr/planete/article/2013/08/15/le-jeune-en-vogue-mais-controverse-est-il-si-bon-pour-la-sante_3443212_3244.html

Les médecins français qui accompagnent des jeûnes :

 https://jeune-et-randonnee.pagesperso-orange.fr/medecins.htm

Infections fongiques invasives

von Lilienfeld-Toal M, Wagener J, Einsele H, Cornely OA, Kurzai O. Invasive Fungal Infection. Dtsch Arztebl Int. 2019 Apr 19;116(16):271-278. doi: 10.3238/arztebl.2019.0271. PMID: 31159914; PMCID: PMC6549129. https://pubmed.ncbi.nlm.nih.gov/31159914/ #Candida #Aspergillus #resistance aux antimycotiques

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Phages et phagothérapie

Dufour et Debarbieux La phagothérapie : Une arme crédible face à l’antibiorésistance

Dublanchet op cit

LA SÉLECTION DE DIANA ALVES

Presque 1500 publications sur les phages jusqu’en 2017.

PUBLICATIONS PLUS RÉCENTES + SÉLECTION

Cheng CM, Wang HJ, Bau HJ, Kuo TT. The primary immunity determinant in modulating the lysogenic immunity of the filamentous bacteriophage. J Mol Biol. 1997;287:867–867. [PubMed] [Google Scholar]

Bacteriophage: Time to Re-Evaluate the Potential of Phage Therapy as a Promising Agent to Control Multidrug-Resistant Bacteria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586887/

Revue médicale suisse 2014

Phage treatment of an aortic graft infected with Pseudomonas aeruginosa
Benjamin K Chan Paul E Turner Samuel Kim Hamid R Mojibian John A Elefteriades Deepak Narayan Evolution, Medicine, and Public Health, Volume 2018, Issue 1, 1 January 2018, Pages 60–66, En ligne

Contemporary Phage Biology: From Classic Models to New Insights
Gal Ofir, Rotem Sorek Revue Cell en vente en ligne

Un site sur la culture des phages-gardiens
La culture des phages : comment les lycéens cultivent des phages-gardiens ; la culture des phages-gardiens pour soigner
Un site sur la pratique de la phagothérapie
Le cours de phagothérapie : une méthode à la fois simple et adaptée aux cas cliniques

C’est plus ou moins une sélection car les documents ne sont pas très nombreux

Publications académiques

Annonces et articles pour 2018Publications, congrès, etc.
Presse avant 2018

Un premier inventaire

Témoignages de patients dans la presse

Une dizaine

the development of phages that target respiratory infections (including Pseudomonas, Burkholderia and Haemophilus) and the developing phages to target Salmonella (Innovate UK/BBSRC funded)

Seal BS Characterization of bacteriophages virulent for Cp …

Chloroquine

Vincent MJ, Bergeron E, Benjannet S, et al. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virol J. 2005;2:69. Published 2005 Aug 22. doi:10.1186/1743-422X-2-69
https://pubmed.ncbi.nlm.nih.gov/16115318/

Keyaerts E, Vijgen L, Maes P, Neyts J, Van Ranst M. In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine. Biochem Biophys Res Commun. 2004;323(1):264–268. doi:10.1016/j.bbrc.2004.08.085
https://pubmed.ncbi.nlm.nih.gov/15351731/

Braga CB, Martins AC, Cayotopa AD, Klein WW, Schlosser AR, da Silva AF, de Souza MN, Andrade BW, Filgueira-Júnior JA, Pinto Wde J, da Silva-Nunes M. Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil). Interdiscip Perspect Infect Dis. 2015;2015:346853. doi: 10.1155/2015/346853. Epub 2015 Aug 18. PMID: 26357512; PMCID: PMC4556080.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556080/

Melles RB, Marmor MF. Pericentral retinopathy and racial differences in hydroxychloroquine toxicity. Ophthalmology. 2015;122(1):110–116. doi:10.1016/j.ophtha.2014.07.018
https://pubmed.ncbi.nlm.nih.gov/25182842/

Golda A, Malek N, Dudek B, Zeglen S, Wojarski J, Ochman M, Kucewicz E, Zembala M, Potempa J, Pyrc K. Infection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells. J Gen Virol. 2011 Jun;92(Pt 6):1358-1368. doi: 10.1099/vir.0.028381-0. Epub 2011 Feb 16. PMID: 21325482; PMCID: PMC3168281.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168281/

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Alerte WikiPédia et Seconde médecine

Les bactéries multirésistantes aux antibiotiques

  • Escherichia coli (26%), qui vit naturellement dans les intestins. 17,6% des souches sont résistantes aux céphalosporines de 3e génération (C3G) et 1,4% aux carbapénèmes.
  • Staphylococcus aureus (16%), présent dans la muqueuse du nez, de la gorge et sur le périnée d’environ 15 à 30 % des individus – des sous-espèces sont nommées « mangeuses de chair » 38% des souches sont résistantes à la méticilline
  • Pseudomonas aeruginosa (8,4%), qui se développe dans les sols et en milieu humide (robinets, tuyauteries…). 20% des souches sont résistantes à la ceftazidime ou aux carbapénèmes
  • Streptocoques dont les entérocoques
  • Clostridium difficile
  • Acinetobacter baumannii 
  • Klebsiella pneumoniae 37,7% des souches sont résistantes aux C3G et 2,3% aux carbapénèmes.
  • Les champignons/levures, les virus et les parasites sont beaucoup plus rarement incriminés, représentant respectivement 3,7%, 0,4% et 0,2% des micro-organismes identifiés.

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OMS Antimicrobial resistance

Rapport AMR Lord O’Neill en anglais

Notre analyse du rapport O’Neill en français

FILMS ET VIDÉOS

Une sélection.

SOURCES EXTERNES POUR LES BACTÉRIES MULTIRÉSISTANTES

Une sélection

DIGESTIF – SYSTÈME

DIARRHÉE NOSOCOMIALE ; CLOSTRIDIUM DIFFICILE

Martha Clockie Publications

GANGRÈNE ; CLOSTRIDIUM PERFRINGENS

Seal BS Characterization of bacteriophages virulent for Cp …

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Lyme

Martha Clockie Travaux en cours

MÉLIOÏDOSE ; BURKHOLDERIA PSEUDOMALLEI

Martha Clockie Publications

MUCOVISCIDOSE PSEUDOMONAS AERUGINOSA

Martha Clockie Publications

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Dermato

Acné Ewa Jończyk-Matysiak et col

PSEUDOPESTE AVIAIRE MALADIE DE NEWCASTLE

Une publication

MULTIPATHOLOGIE CAMPYLOBACTER JEJUNI

Martha Clockie Publications

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Yeux

Keratose

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Analyse des pratiques médicales – Première médecine

Dr André Crismer Ces médicaments qui ne guérissent pas https://www.maisonmedicale.org/Ces-medicaments-qui-ne-guerissent.html

R. Legal, C. Pilorge Variabilité des pratiques de prescription des médecins généralistes et ajustement au risque
https://www.ces-asso.org/sites/default/files/Legal_Pilorge_0.pdf

Les cent médicaments les plus prescrits https://www.doctissimo.fr/asp/medicaments/les-medicaments-les-plus-prescrits.htm

ANSM Analyse des ventes de médicaments en France en 2013 https://ansm.sante.fr/var/ansm_site/storage/original/application/3df7b99f8f4c9ee634a6a9b094624341.pdf

L’ANSM interdit l’utilisation de 3 plantes et 26 substances actives dans les préparations à
visée amaigrissante réalisées en pharmacie #Garcinia cambodgia #Citrus aurantium #Hoodia gordonii https://ansm.sante.fr/var/ansm_site/storage/original/application/d4d8f6c5e30880cc0a575c5e0806f45a.pdf

Pollution par les médicaments http://sesoignersanspolluer.com/wp-content/uploads/2019/03/gazette-n%C2%B01-compress%C3%A9.pdf

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MiDa

Anne-Sophie Limonier La Phytothérapie de demain : les plantes médicinales au cœur de la pharmacie https://dumas.ccsd.cnrs.fr/dumas-01840619/document

Pierre Grenand, Christian Moretti, Henri Jacquemin, Marie-Françoise Prévost Pharmacopées traditionnelles en Guyane : créoleswayapi & palikur
Le livre format papier
Le pdf

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Vésicule biliaire et terrain immunitaire

Parkanzky M, Grimes J, Schmiedt C, Secrest S, Bugbee A. Long-term survival of dogs treated for gallbladder mucocele by cholecystectomy, medical management, or both. J Vet Intern Med. 2019 Sep;33(5):2057-2066. doi: 10.1111/jvim.15611. Epub 2019 Sep 6. PMID: 31490022; PMCID: PMC6766501. https://pubmed.ncbi.nlm.nih.gov/31490022/ #ablation vésicule biliaire

Zhang Y, Liu H, Li L, Ai M, Gong Z, He Y, Dong Y, Xu S, Wang J, Jin B, Liu J, Teng Z. Cholecystectomy can increase the risk of colorectal cancer: A meta-analysis of 10 cohort studies. PLoS One. 2017 Aug 3;12(8):e0181852. doi: 10.1371/journal.pone.0181852. Erratum in: PLoS One. 2018 Jan 17;13(1):e0191587. PMID: 28771518; PMCID: PMC5542607. https://pubmed.ncbi.nlm.nih.gov/28771518/ #ablation vésicule biliaire

Pak M, Lindseth G. Risk Factors for Cholelithiasis. Gastroenterol Nurs. 2016 Jul-Aug;39(4):297-309. doi: 10.1097/SGA.0000000000000235. PMID: 27467059. https://pubmed.ncbi.nlm.nih.gov/27467059/ #risques des calculs biliaires #prévention

Constance E. Ruhl, James E. Everhart Gallstone Disease Is Associated With Increased Mortality in the United States Gastroenterology February 2011 https://www.gastrojournal.org/article/S0016-5085(10)01611-2/fulltext

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Purge thérapeutique

Kaur M, Chandola H. Role of Virechana Karma in cure and prevention of recurrence of Vicharchika (Eczema). Ayu. 2012 Oct;33(4):505-10. doi: 10.4103/0974-8520.110526. PMID: 23723667; PMCID: PMC3665194.

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Probiotiques

Pais P, Almeida V, Yılmaz M, Teixeira MC. Saccharomyces boulardii: What Makes It Tick as Successful Probiotic? J Fungi (Basel). 2020 Jun 4;6(2):78. doi: 10.3390/jof6020078. PMID: 32512834; PMCID: PMC7344949.

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Fibromyalgie

Fibromyalgie et suicide sur PubMed

Douleur physique et suicide sur PubMed

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Suicide

Maladie chronique et suicide sur PubMed

Psoriasis

Asthme

Allergies

Migraine

Polyarthrite rhumatoïde

HIV

& Alerte WikiPédia et Seconde médecine

Dysbiose intestinale WikiPédia

Koliarakis I, Messaritakis I, Nikolouzakis TK, Hamilos G, Souglakos J, Tsiaoussis J. Oral Bacteria and Intestinal Dysbiosis in Colorectal Cancer. Int J Mol Sci. 2019 Aug 25;20(17):4146. doi: 10.3390/ijms20174146. PMID: 31450675; PMCID: PMC6747549.

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Acidose Acidémie WikiPédia

Ibrahim-Hashim A, Estrella V. Acidosis and cancer: from mechanism to neutralization. Cancer Metastasis Rev. 2019 Jun;38(1-2):149-155. doi: 10.1007/s10555-019-09787-4. PMID: 30806853; PMCID: PMC6625834.

&leaky

Perméabilité intestinale WikiPédia

Hyperperméabilité intestinale WikiPédia

Usuda H, Okamoto T, Wada K. Leaky Gut: Effect of Dietary Fiber and Fats on Microbiome and Intestinal Barrier. Int J Mol Sci. 2021 Jul 16;22(14):7613. doi: 10.3390/ijms22147613. PMID: 34299233; PMCID: PMC8305009.

& Alerte WikiPédia et Seconde médecine

Inflammation et développement des cellules malignes

Singh N, Baby D, Rajguru JP, Patil PB, Thakkannavar SS, Pujari VB. Inflammation and cancer. Ann Afr Med. 2019 Jul-Sep;18(3):121-126. doi: 10.4103/aam.aam_56_18. PMID: 31417011; PMCID: PMC6704802.

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Respiration cellulaire WikiPédia
Le stress oxydant ou stress oxydatif WikiPédia
Réaction d’oxydoréduction Rédox Wikipédia

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Neurotransmetteurs, psychobiologie, immunité, inflammation

Neurotransmetteur WikiPédia

Trouble de stress post-traumatique WikiPédia

Ernest Rossi Psychobiologie de la guérison Éd. Le Souffle d’or, 2002 (ISBN 2840582090)
Robert Dilts & Patricia Dilts en anglais
Rossi & Dilts en anglais BeeCourse Audio

Jiang SH, Hu LP, Wang X, Li J, Zhang ZG. Neurotransmitters: emerging targets in cancer. Oncogene. 2020 Jan;39(3):503-515. doi: 10.1038/s41388-019-1006-0. Epub 2019 Sep 16. PMID: 31527667.

Aline Sarradon-Eck et Coralie Caudullo Le décodage biologique. Diffusion d’une nouvelle médecine non-conventionnelle contre le cancer Open Edition Journals

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Lait et produit laitiers

Fraser GE, Jaceldo-Siegl K, Orlich M, Mashchak A, Sirirat R, Knutsen S. Dairy, soy, and risk of breast cancer: those confounded milks. Int J Epidemiol. 2020 Oct 1;49(5):1526-1537. doi: 10.1093/ije/dyaa007. PMID: 32095830; PMCID: PMC8453418.

Mozaffarian D. Dairy Foods, Obesity, and Metabolic Health: The Role of the Food Matrix Compared with Single Nutrients. Adv Nutr. 2019 Sep 1;10(5):917S-923S. doi: 10.1093/advances/nmz053. PMID: 31518410; PMCID: PMC6743828.

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Alimentation et bonne santé

Gul K, Singh AK, Jabeen R. Nutraceuticals and Functional Foods: The Foods for the Future World. Crit Rev Food Sci Nutr. 2016 Dec 9;56(16):2617-27. doi: 10.1080/10408398.2014.903384. PMID: 25629711.

&alleinto

Allergie et intolérance alimentaire

Muthukumar J, Selvasekaran P, Lokanadham M, Chidambaram R. Food and food products associated with food allergy and food intolerance – An overview. Food Res Int. 2020 Dec;138(Pt B):109780. doi: 10.1016/j.foodres.2020.109780. Epub 2020 Oct 15. PMID: 33288166.

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Antilope – analogie

Das A, Katole S, Choubey M, Gupta SP, Saini M, Kumar V, Swarup D. Feed consumption, diet digestibility and mineral utilization in captive blackbuck (Antelope cervicapra) fed different levels of concentrates. J Anim Physiol Anim Nutr (Berl). 2013 Feb;97(1):80-90. doi: 10.1111/j.1439-0396.2011.01245.x. Epub 2011 Nov 17. Erratum in: J Anim Physiol Anim Nutr (Berl). 2013 Oct;97(5):1006. PMID: 22093070.

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Vitamines

Choline – famille des vitamines B

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Sucre

Lenoir M, Serre F, Cantin L, Ahmed SH. Intense sweetness surpasses cocaine reward. PLoS One. 2007 Aug 1;2(8):e698. doi: 10.1371/journal.pone.0000698. PMID: 17668074; PMCID: PMC1931610.

Ahmed SH, Guillem K, Vandaele Y. Sugar addiction: pushing the drug-sugar analogy to the limit. Curr Opin Clin Nutr Metab Care. 2013 Jul;16(4):434-9. doi: 10.1097/MCO.0b013e328361c8b8. PMID: 23719144.

&globcell

Revue globale sur les plantes anti-cellules malignes

Mazzio EA, Soliman KF. In vitro screening for the tumoricidal properties of international medicinal herbs. Phytother Res. 2009 Mar;23(3):385-98. doi: 10.1002/ptr.2636. PMID: 18844256; PMCID: PMC2650746.

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Garcinia cambodgia

Nabandith V, Suzui M, Morioka T, Kaneshiro T, Kinjo T, Matsumoto K, Akao Y, Iinuma M, Yoshimi N. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac J Cancer Prev. 2004 Oct-Dec;5(4):433-8. PMID: 15546251.

Suksamrarn S, Komutiban O, Ratananukul P, Chimnoi N, Lartpornmatulee N, Suksamrarn A. Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana. Chem Pharm Bull (Tokyo). 2006 Mar;54(3):301-5. doi: 10.1248/cpb.54.301. PMID: 16508181.

Matsumoto K, Akao Y, Kobayashi E, Ito T, Ohguchi K, Tanaka T, Iinuma M, Nozawa Y. Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-inducing effect against human leukemia cell lines. Biol Pharm Bull. 2003 Apr;26(4):569-71. doi: 10.1248/bpb.26.569. PMID: 12673047.

Liu W, Guo QL, You QD, Zhao L, Gu HY, Yuan ST. Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823. World J Gastroenterol. 2005 Jun 28;11(24):3655-9. doi: 10.3748/wjg.v11.i24.3655. PMID: 15968715; PMCID: PMC4316011.

Zhang HZ, Kasibhatla S, Wang Y, Herich J, Guastella J, Tseng B, Drewe J, Cai SX. Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. Bioorg Med Chem. 2004 Jan 15;12(2):309-17. doi: 10.1016/j.bmc.2003.11.013. PMID: 14723951.

Guo QL, You QD, Wu ZQ, Yuan ST, Zhao L. General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice. Acta Pharmacol Sin. 2004 Jun;25(6):769-74. PMID: 15169630.

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Surdité, audition

Mudry A, Santa Maria P, Jackler RK. Ossicular calisthenics: Pneumomassage of the tympanic membrane. Laryngoscope. 2016 May;126(5):1180-6. doi: 10.1002/lary.25556. Epub 2015 Sep 30. PMID: 26421977.


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